The Yod1 Antibody - N-terminal region (ARP67915_P050) from Aviva Systems Biology is a Rabbit Polyclonal antibody. This antibody recognizes Mouse antigen. The Yod1 Antibody - N-terminal region (ARP67915_P050) has been validated for the following applications: Western Blot.
Description
Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. Yod1 may act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Yod1 mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. It is able to cleave both polyubiquitin and di-ubiquitin